SCHEMBL7563577

SCHEMBL7563577

FC(F)(F)C(F)(F)N(C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7796380 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL7560330 1.00 LMNA (0.38) LMNACA1CA2MMP1MMP2
SCHEMBL22032019 0.97 LMNA (0.33) LMNA
SCHEMBL11421524 0.94 LMNA (0.42) LMNACA1CA2MMP1MMP2
SCHEMBL17111382 0.94 LMNA (0.42) LMNACA1CA2MMP1MMP2
SCHEMBL195985 0.94 LMNA (0.42) LMNACA1CA2MMP1MMP2
SCHEMBL78572 0.94 LMNA (0.42) LMNACA1CA2MMP1MMP2
SCHEMBL14717610 0.94 LMNA (0.42) LMNACA1CA2MMP1MMP2
SCHEMBL480135 0.94 LMNA (0.42) LMNACA1CA2MMP1MMP2
SCHEMBL36219 0.90 LMNA (0.37) LMNACA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0033402-B1 PERFUSATE FOR PRESERVING ORGAN TO BE TRANSPLANTED AND PRESERVING METHOD The Green Cross Corporation (JP) 1983-09-07 EP claimed
EP-0033402-A1 Perfusate for preserving organ to be transplanted and preserving method The Green Cross Corporation (JP) 1981-08-12 EP claimed
US-4186253-A RINGER'S SOLUTION WITH INCREASED POTASSIUM ION, ALBUMIN, PERFLUOROCARBON COMPOUND, EMULSIFIER THE GREEN CROSS CORPORATION (JP) 1980-01-29 US claimed
US-3962439-A PERFLUOROCARBON COMPOUNDS THE GREEN CROSS CORPORATION (JA) 1976-06-08 US claimed
US-20020164379-A1 Oxygen-containing ophthalmic composition ROHTO PHARMACEUTICAL CO., LTD. (JP) 2002-11-07 US disclosed
US-5262442-A Fluosol for injection for oxygen transport ALPHA THERAPEUTIC CORPORATION (US) 1993-11-16 US disclosed
EP-0548601-A1 Process for rapid thawing and storage of frozen fluorocarbon emulsion, and resultant product ALPHA THERAPEUTIC CORPORATION (US) 1993-06-30 EP disclosed
EP-0282949-B1 CONCENTRATED STABLE FLUORCHEMICAL AQUEOUS EMULSIONS AIR PRODUCTS AND CHEMICALS, INC. (US) 1992-05-20 EP disclosed
US-5114932-A Hyperosmolar oxyreplete hemosubstitute RUNGE THOMAS M (US) 1992-05-19 US disclosed
US-4895876-A ARTIFICIAL BLOOD, ORGAN PRESERVATION AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-01-23 US disclosed
EP-0033402-B1 PERFUSATE FOR PRESERVING ORGAN TO BE TRANSPLANTED AND PRESERVING METHOD The Green Cross Corporation (JP) 1983-09-07 EP disclosed
EP-0033402-A1 Perfusate for preserving organ to be transplanted and preserving method The Green Cross Corporation (JP) 1981-08-12 EP disclosed
US-4186253-A RINGER'S SOLUTION WITH INCREASED POTASSIUM ION, ALBUMIN, PERFLUOROCARBON COMPOUND, EMULSIFIER THE GREEN CROSS CORPORATION (JP) 1980-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020164379-A1 Oxygen-containing ophthalmic composition OGFOD1, HIF1A, HAO2 LMNA 3995/4885CA1 2962/4885CA2 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.