Quinoline

Quinoline

SCHEMBL14717992

O=S(=O)(O)CO.c1ccc2ncccc2c1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.65
KDM4E B2RXH2 4/20 0.44
ALOX12 P18054 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CASP1 P29466 2/20 0.44
CASP7 P55210 1/20 0.44
NPC1 O15118 2/20 0.42
POLB P06746 2/20 0.42
RAB9A P51151 1/20 0.42
CYP3A4 P08684 2/20 0.41
MAPT P10636 3/20 0.41
PDE10A Q9Y233 1/20 0.41
NAMPT P43490 1/20 0.40
BCAT1 P54687 1/20 0.40
HTT P42858 4/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
NR4A2 P43354 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL21535 0.90 ALDH1A1 (0.74) ALDH1A1KDM4EALOX12MEN1KMT2A
Quinoline SCHEMBL29710686 0.90 ALDH1A1 (0.74) ALDH1A1KDM4EALOX12MEN1KMT2A
Quinoline SCHEMBL28261411 0.90 ALDH1A1 (0.74) ALDH1A1KDM4EALOX12MEN1KMT2A
Quinoline SCHEMBL5874241 0.90 ALDH1A1 (0.74) ALDH1A1KDM4EALOX12MEN1KMT2A
Quinoline SCHEMBL28142303 0.90 ALDH1A1 (0.74) ALDH1A1KDM4EALOX12MEN1KMT2A
Quinoline SCHEMBL336070 0.89 ALDH1A1 (0.65) ALDH1A1KDM4EALOX12MEN1KMT2A
Quinoline SCHEMBL27476711 0.89 ALDH1A1 (0.65) ALDH1A1KDM4EALOX12MEN1KMT2A
Quinoline SCHEMBL29192334 0.88 ALDH1A1 (0.71) ALDH1A1KDM4EALOX12MEN1KMT2A
Quinoline SCHEMBL20972298 0.88 ALDH1A1 (0.71) ALDH1A1KDM4EALOX12MEN1KMT2A
Quinoline SCHEMBL20972296 0.88 ALDH1A1 (0.71) ALDH1A1KDM4EALOX12MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103763947-B Method and composition for protecting beverages from heat and light stress 百事可乐公司 2018-02-13 CN disclosed
CN-103763947-A Method and composition for protecting beverages from heat and light stress PEPSICO INC 2014-04-30 CN disclosed
US-20130052315-A1 Methods and Compositions for Protecting Beverages From Heat and Light Stress PEPSICO, INC. (US) 2013-02-28 US disclosed