Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 11/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 12/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12799208 | 0.87 | RAB9A (0.65) | PTGS1PTGS2KDM4EMAPTNPSR1 | |
| SCHEMBL1662102 | 0.83 | KDM4E (0.63) | PTGS1PTGS2KDM4EMAPTNPSR1 | |
| SCHEMBL1494782 | 0.79 | KDM4E (0.75) | PTGS1PTGS2KDM4EMAPTNPSR1 | |
| SCHEMBL4728069 | 0.78 | NPC1 (0.67) | PTGS1PTGS2KDM4EMAPTNPSR1 | |
| SCHEMBL19322176 | 0.77 | KDM4E (0.82) | PTGS1PTGS2KDM4EMAPTNPSR1 | |
| SCHEMBL1661152 | 0.76 | RAB9A (0.55) | PTGS1PTGS2KDM4EMAPTNPSR1 | |
| SCHEMBL3440250 | 0.76 | NPC1 (0.67) | PTGS1PTGS2KDM4EMAPTNPSR1 | |
| SCHEMBL30366944 | 0.76 | RAB9A (0.69) | PTGS1PTGS2KDM4EMAPTNPSR1 | |
| SCHEMBL1494939 | 0.76 | ALDH1A1 (0.77) | PTGS1PTGS2KDM4EMAPTNPSR1 | |
| SCHEMBL13325909 | 0.76 | RAB9A (0.83) | PTGS1PTGS2KDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491009-B1 | CYCLOPENTANECARBOXAMIDE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INT (DE) | 2017-07-05 | — | — | EP | disclosed |
| US-8614238-B2 | Cyclopentanecarboxamide derivatives, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-12-24 | — | — | US | disclosed |
| US-20130053412-A1 | Cyclopentanecarboxamide derivatives, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053412-A1 | Cyclopentanecarboxamide derivatives, medicaments containing such compounds and their use | CPT1A, FASN, CES1 | PTGS1 11/4885PTGS2 97/4885KDM4E 2941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.