Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.67 |
| ▸ | RAB9A | P51151 | 12/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | HPGD | P15428 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662102 | 0.88 | KDM4E (0.63) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL1494782 | 0.86 | KDM4E (0.75) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL1494939 | 0.82 | ALDH1A1 (0.77) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL4727605 | 0.82 | MAPT (0.60) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL19322176 | 0.81 | KDM4E (0.82) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL4725484 | 0.81 | ALDH1A1 (0.67) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL12799208 | 0.78 | RAB9A (0.65) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| Trifluoroacetic Acid SCHEMBL14719213 | 0.78 | PTGS1 (0.57) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL1494571 | 0.78 | KDM4E (0.77) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL30366944 | 0.78 | RAB9A (0.69) | NPC1RAB9ASMN1; SMN2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029152-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |