Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14716104 | 1.00 | BCHE (0.31) | BCHECYP4F2CYP4A11MEN1KMT2A | |
| SCHEMBL14716101 | 1.00 | BCHE (0.31) | BCHECYP4F2CYP4A11MEN1KMT2A | |
| SCHEMBL14716102 | 1.00 | BCHE (0.31) | BCHECYP4F2CYP4A11MEN1KMT2A | |
| SCHEMBL20218704 | 1.00 | BCHE (0.31) | BCHECYP4F2CYP4A11MEN1KMT2A | |
| SCHEMBL14715920 | 0.91 | MEN1 (0.33) | BCHEMEN1KMT2A | |
| SCHEMBL14715919 | 0.91 | MEN1 (0.33) | BCHEMEN1KMT2A | |
| SCHEMBL14715917 | 0.91 | MEN1 (0.33) | BCHEMEN1KMT2A | |
| SCHEMBL20218810 | 0.91 | MEN1 (0.33) | BCHEMEN1KMT2A | |
| SCHEMBL14715871 | 0.84 | CYP4F2 (0.32) | BCHECYP4F2CYP4A11MEN1KMT2A | |
| SCHEMBL20218870 | 0.84 | CYP4F2 (0.32) | BCHECYP4F2CYP4A11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2581361-B1 | Intermediates for the synthesis of benzindene prostaglandins and preparations thereof | CHIROGATE INT INC (TW) | 2018-06-06 | — | — | EP | disclosed |
| US-8658837-B2 | Intermediates for the synthesis of benzindene prostaglandins and preparations thereof | CHIROGATE INTERNATIONAL INC. (TW) | 2014-02-25 | — | — | US | disclosed |
| US-20130317245-A1 | INTERMEDIATES FOR THE SYNTHESIS OF BENZINDENE PROSTAGLANDINS AND PREPARATIONS THEREOF | CHIROGATE INTERNATIONAL INC. (TW) | 2013-11-28 | — | — | US | disclosed |
| US-8524939-B2 | Intermediates for the synthesis of benzindene prostaglandins and preparations thereof | CHIROGATE INTERNATIONAL INC. (TW) | 2013-09-03 | — | — | US | disclosed |
| EP-2581361-A1 | Intermediates for the synthesis of benzindene prostaglandins and preparations thereof | Chirogate International Inc. (TW) | 2013-04-17 | — | — | EP | disclosed |
| US-20130053581-A1 | INTERMEDIATES FOR THE SYNTHESIS OF BENZINDENE PROSTAGLANDINS AND PREPARATIONS THEREOF | CHIROGATE INTERNATIONAL INC. | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053581-A1 | INTERMEDIATES FOR THE SYNTHESIS OF BENZINDENE PROSTAGLANDINS AND PREPARATIONS THEREOF | PTGIS, PTGES, PTGS1 | BCHE 1585/4885CYP4F2 264/4885CYP4A11 128/4885 |
| US-20130317245-A1 | INTERMEDIATES FOR THE SYNTHESIS OF BENZINDENE PROSTAGLANDINS AND PREPARATIONS THEREOF | PTGIS, PTGES, PTGS1 | BCHE 1585/4885CYP4F2 264/4885CYP4A11 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.