SCHEMBL14729331

SCHEMBL14729331

CCOC(=O)CCCC(=O)N(C)[C@@H](CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
CYP1A2 P05177 2/20 0.37
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
CTSK P43235 2/20 0.34
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
NR1I2 O75469 1/20 0.32
PGR P06401 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
PTGS2 P35354 1/20 0.32
PDE4D Q08499 1/20 0.32
ALOX5 P09917 1/20 0.32
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
GAA P10253 1/20 0.31
SMYD3 Q9H7B4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18145528 1.00 POLB (0.39) POLBCYP1A2KMT2AL3MBTL1CTSK
SCHEMBL14454329 0.80 LTA4H (0.35)
SCHEMBL27527957 0.80 CYP1A2 (0.55) POLBCYP1A2KMT2AL3MBTL1CYP2C9
SCHEMBL5409578 0.78 L3MBTL1 (0.35) POLBCYP1A2KMT2AL3MBTL1CYP2C9
SCHEMBL14777935 0.76 L3MBTL1 (0.39) POLBCYP1A2KMT2AL3MBTL1CTSK
SCHEMBL14777936 0.76 L3MBTL1 (0.39) POLBCYP1A2KMT2AL3MBTL1CTSK
SCHEMBL27643221 0.76 CYP1A2 (0.55) CYP1A2KMT2AL3MBTL1RAB9ANR1I2
SCHEMBL14719877 0.75 CYP1A2 (0.41) POLBCYP1A2KMT2AL3MBTL1RAB9A
SCHEMBL15055158 0.75 CYP1A2 (0.53) CYP1A2KMT2ANR1I2PGRADORA3
SCHEMBL26648449 0.75 CYP1A2 (0.53) CYP1A2KMT2ANR1I2PGRADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-20180258134-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2018-09-13 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 POLB 3330/4885CYP1A2 4839/4885KMT2A 3251/4885
US-20180258134-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 POLB 3330/4885CYP1A2 4839/4885KMT2A 3251/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 POLB 3330/4885CYP1A2 4839/4885KMT2A 3251/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 POLB 3769/4885CYP1A2 2802/4885KMT2A 2592/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 POLB 3330/4885CYP1A2 4839/4885KMT2A 3251/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 POLB 3330/4885CYP1A2 4839/4885KMT2A 3251/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 POLB 3904/4885CYP1A2 3017/4885KMT2A 2897/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 POLB 3330/4885CYP1A2 4839/4885KMT2A 3251/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 POLB 3330/4885CYP1A2 4839/4885KMT2A 3251/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 POLB 3330/4885CYP1A2 4839/4885KMT2A 3251/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 POLB 3330/4885CYP1A2 4839/4885KMT2A 3251/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 POLB 3330/4885CYP1A2 4839/4885KMT2A 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.