Sugi Predict

Sugi Predict / Compounds / SCHEMBL14719940

SCHEMBL14719940

SCHEMBL14719940

O=C(O)CC[C@H](NC(=O)C[C@H](NC(=O)CCCc1ccc([N+](=O)[O-])cc1)C(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 4/20 0.48
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ NPC1 O15118 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ MME P08473 1/20 0.44
▸ MMP2 P08253 1/20 0.42
▸ DGAT1 O75907 1/20 0.42
▸ DHFR P00374 1/20 0.42
▸ HDAC3 O15379 1/20 0.41
▸ HDAC1 Q13547 1/20 0.41
▸ HDAC2 Q92769 1/20 0.41
▸ HDAC8 Q9BY41 1/20 0.41
▸ ALB P02768 2/20 0.41
▸ TGM2 P21980 1/20 0.41
▸ NAALAD2 Q9Y3Q0 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14720022 1.00 FOLH1 (0.48) FOLH1MEN1KMT2ANPC1RAB9A
SCHEMBL14729476 0.84 FOLH1 (0.60) FOLH1
SCHEMBL18145804 0.84 FOLH1 (0.60) FOLH1
SCHEMBL9386073 0.82 KMT2A (0.55) FOLH1MEN1KMT2AMMP2NAALAD2
SCHEMBL14729380 0.81 ALDH1A1 (0.57) KMT2ARAB9AALDH1A1CYP2C9HPGD
SCHEMBL18145530 0.81 ALDH1A1 (0.57) KMT2ARAB9AALDH1A1CYP2C9HPGD
SCHEMBL4919361 0.79 NAALAD2 (0.61) FOLH1HDAC3HDAC1HDAC2HDAC8
SCHEMBL4919365 0.79 NAALAD2 (0.61) FOLH1HDAC3HDAC1HDAC2HDAC8
SCHEMBL4925430 0.78 ALB (0.50) FOLH1HDAC1ALBNAALAD2
SCHEMBL18725625 0.78 ALB (0.62) FOLH1ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 — — US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 — — US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 — — US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 — — US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 — — US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 — — US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 — — US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 — — US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 — — US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 — — US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 — — US disclosed
US-20180258134-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2018-09-13 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 — — WO disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885KMT2A 3251/4885
US-20180258134-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885KMT2A 3251/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885KMT2A 3251/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 FOLH1 4/4885MEN1 235/4885KMT2A 2592/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885KMT2A 3251/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885KMT2A 3251/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 FOLH1 4/4885MEN1 197/4885KMT2A 2897/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885KMT2A 3251/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885KMT2A 3251/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885KMT2A 3251/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885KMT2A 3251/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885KMT2A 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.