SCHEMBL4925430

SCHEMBL4925430

Cc1ccc(CCCC(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALB P02768 3/20 0.50
FOLH1 Q04609 8/20 0.49
NAALAD2 Q9Y3Q0 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
GART P22102 1/20 0.46
ATIC P31939 1/20 0.46
NOD1 Q9Y239 1/20 0.46
HDAC1 Q13547 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4925425 1.00 ALB (0.50) ALBFOLH1NAALAD2SMN1; SMN2GART
SCHEMBL4919361 0.87 NAALAD2 (0.61) FOLH1NAALAD2SMN1; SMN2HDAC1
SCHEMBL4919365 0.87 NAALAD2 (0.61) FOLH1NAALAD2SMN1; SMN2HDAC1
SCHEMBL18725624 0.86 ALB (0.62) ALBFOLH1
SCHEMBL18725625 0.86 ALB (0.62) ALBFOLH1
SCHEMBL29798933 0.86 FOLH1 (0.65) FOLH1
SCHEMBL2330781 0.86 ALDH1A1 (0.54) ALB
SCHEMBL20100671 0.83 ITGB3 (0.47) ALBNOD1HDAC1
SCHEMBL18145804 0.82 FOLH1 (0.60) FOLH1
SCHEMBL14729476 0.82 FOLH1 (0.60) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2008-10-30 US claimed
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 ALB 1078/4885FOLH1 1671/4885NAALAD2 1636/4885
US-20070066646-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 ALB 1003/4885FOLH1 1974/4885NAALAD2 1846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.