Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.32 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.32 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.32 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.32 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.32 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.32 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.32 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.32 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661734 | 0.86 | HPGD (0.50) | HPGDSTK17BHDAC8HDAC2SRD5A1 | |
| SCHEMBL20587570 | 0.86 | OGA (0.40) | HPGDHRH3HTR2CSRD5A1TSHR | |
| SCHEMBL10394171 | 0.82 | HPGD (0.47) | HPGDSTK17BHDAC8HDAC2HRH3 | |
| SCHEMBL14720582 | 0.81 | HRH3 (0.37) | HRH3HTR2CPRKACAPRKACGPRKACB | |
| SCHEMBL14720535 | 0.81 | HRH3 (0.36) | HPGDHRH3HTR2CSRD5A1TSHR | |
| SCHEMBL18991965 | 0.81 | IGF1R (0.47) | HPGDHRH3HTR2C | |
| Hydrochloric Acid SCHEMBL4887847 | 0.80 | OGA (0.36) | HPGDHRH3HTR2CSRD5A1HTR2B | |
| SCHEMBL7039734 | 0.77 | HDAC3 (0.43) | HRH3HTR2CTSHR | |
| SCHEMBL14730978 | 0.75 | MAOA (0.43) | HRH3HTR2CHTR2BPRKACAPRKACG | |
| SCHEMBL12076004 | 0.75 | PRKACA (0.41) | HRH3HTR2CHTR2BADCY6ADCY3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |