Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18991965 | 0.81 | IGF1R (0.47) | HRH3ALDH1A1HTR2C | |
| SCHEMBL14731053 | 0.80 | LTA4H (0.40) | HRH3ACHETSHRBCHEPARP1 | |
| SCHEMBL14720582 | 0.77 | HRH3 (0.37) | HRH3TAAR1HTR2C | |
| SCHEMBL14720535 | 0.77 | HRH3 (0.36) | HRH3ALDH1A1TSHRHTR2C | |
| SCHEMBL14720429 | 0.77 | HPGD (0.47) | HRH3TSHRHTR2C | |
| Hydrochloric Acid SCHEMBL4887847 | 0.76 | OGA (0.36) | HRH3HTR2C | |
| SCHEMBL20587570 | 0.75 | OGA (0.40) | HRH3ALDH1A1TSHRHTR2C | |
| SCHEMBL14720714 | 0.73 | HDAC6 (0.39) | HDAC3HDAC6MMP9 | |
| Hydrochloric Acid SCHEMBL4881733 | 0.73 | KMT2A (0.47) | HRH3HTR2C | |
| SCHEMBL3282829 | 0.72 | HRH3 (0.51) | HRH3HTR2CPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060162-B1 | URETHANES DERIVED FROM AZACYCLOALKANES, THIO AND DITHIO ANALOGUES, PRODUCTION AND USE THEREOF AS 2,3 EPOXYSQUALENE LANESTEROL CYCLASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-6339096-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERLIPIDAEMIAS, HYPERCHOLESTEROLAEMIAS AND ATHEROSCLEROSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-01-15 | — | — | US | disclosed |
| CN-1281434-A | Urethanes derived from azacycloalkanes, thio and dithio analogues, production and use thereof as 2,3 epoxysqualene lanesterol cyclase inhibitors | BOEHRINGER INGELHEIM PHARMA (DE) | 2001-01-24 | — | — | CN | disclosed |