Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
| ▸ | PRKACB | P22694 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720429 | 0.81 | HPGD (0.47) | HRH3HTR2CTSHRPRKACAPRKACG | |
| SCHEMBL14720582 | 0.81 | HRH3 (0.37) | HRH3HTR2CPRKACAPRKACGPRKACB | |
| SCHEMBL18991965 | 0.81 | IGF1R (0.47) | HRH3HTR2CALDH1A1HPGDIGF1R | |
| Hydrochloric Acid SCHEMBL4887847 | 0.80 | OGA (0.36) | HRH3HTR2CPRKACAPRKACGPRKACB | |
| SCHEMBL20587570 | 0.79 | OGA (0.40) | HRH3HTR2CALDH1A1TSHRSRD5A1 | |
| SCHEMBL14730978 | 0.79 | MAOA (0.43) | HRH3HTR2CPRKACAPRKACGPRKACB | |
| SCHEMBL7039734 | 0.77 | HDAC3 (0.43) | HRH3HTR2CALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL14721151 | 0.77 | HTR2C (0.43) | HRH3HTR2CPRKACAPRKACGPRKACB | |
| SCHEMBL12076004 | 0.75 | PRKACA (0.41) | HRH3HTR2CPRKACAPRKACGPRKACB | |
| SCHEMBL20015685 | 0.75 | IKBKB (0.48) | HRH3HTR2CALDH1A1PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |