Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720551 | 0.84 | ALDH1A1 (0.56) | ALDH1A1POLBSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL14720724 | 0.81 | ALDH1A1 (0.58) | ALDH1A1POLBSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL14720497 | 0.81 | RAB9A (0.45) | ALDH1A1SMN1; SMN2MAPK1RAB9ATDP1 | |
| SCHEMBL14720484 | 0.79 | ALDH1A1 (0.58) | ALDH1A1POLBSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL63892 | 0.78 | ALDH1A1 (0.63) | ALDH1A1POLBSMN1; SMN2MAPK1FDFT1 | |
| SCHEMBL14720723 | 0.78 | KDM2B (0.38) | ALDH1A1 | |
| SCHEMBL2819437 | 0.76 | HRH3 (0.56) | ALDH1A1POLBMAPK1 | |
| SCHEMBL6135228 | 0.76 | ALDH1A1 (0.67) | ALDH1A1POLBSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL14721398 | 0.75 | L3MBTL3 (0.35) | ALDH1A1 | |
| SCHEMBL6134915 | 0.75 | ALDH1A1 (0.65) | ALDH1A1POLBSMN1; SMN2MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |