Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 9/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14721345 | 0.99 | SRD5A2 (0.57) | SRD5A2MAPTHPGDHTTSRD5A1 | |
| SCHEMBL14720637 | 0.85 | L3MBTL3 (0.62) | ALDH1A1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL14720988 | 0.82 | SRD5A2 (0.49) | SRD5A2HPGDALDH1A1HRH3 | |
| SCHEMBL14720518 | 0.82 | HRH3 (0.46) | ALDH1A1L3MBTL3L3MBTL1MBTD1HRH3 | |
| SCHEMBL14720551 | 0.81 | ALDH1A1 (0.56) | MAPTHPGDHTTALDH1A1 | |
| SCHEMBL14720647 | 0.81 | HRH3 (0.43) | SRD5A2OGAL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL14721918 | 0.79 | HDAC6 (0.47) | SRD5A2HRH3 | |
| SCHEMBL14720608 | 0.79 | HRH3 (0.43) | SRD5A2L3MBTL3L3MBTL1MBTD1HRH3 | |
| SCHEMBL14721400 | 0.79 | SRD5A2 (0.48) | SRD5A2SRD5A1ALDH1A1OGAL3MBTL3 | |
| SCHEMBL14721067 | 0.78 | SRD5A2 (0.42) | SRD5A2HPGDSRD5A1ALDH1A1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |