Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720731 | 0.84 | ALDH1A1 (0.45) | HRH3KCNH2ALDH1A1MAPTHPGD | |
| SCHEMBL14721402 | 0.82 | MAPT (0.44) | SRD5A2HRH3ALDH1A1L3MBTL3MAPT | |
| SCHEMBL14722546 | 0.80 | USP2 (0.45) | SRD5A2HRH3HPGD | |
| SCHEMBL14720817 | 0.76 | SRD5A2 (0.43) | SRD5A2HRH3ALDH1A1LMNA | |
| SCHEMBL14721060 | 0.76 | KCNH2 (0.43) | SRD5A2HRH3KCNH2ALDH1A1HPGD | |
| SCHEMBL14720486 | 0.76 | NAMPT (0.38) | SRD5A2HRH3ALDH1A1HPGD | |
| SCHEMBL14720710 | 0.75 | HRH3 (0.56) | HRH3L3MBTL3 | |
| SCHEMBL14721508 | 0.75 | HRH3 (0.38) | SRD5A2HRH3L3MBTL3 | |
| SCHEMBL14731157 | 0.74 | SRD5A2 (0.37) | SRD5A2HRH3ALDH1A1L3MBTL3HPGD | |
| SCHEMBL14720887 | 0.73 | POLB (0.52) | ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |