Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 15/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21795758 | 0.81 | HRH3 (0.48) | OGA | |
| SCHEMBL14720435 | 0.80 | MCHR1 (0.37) | — | |
| SCHEMBL14720708 | 0.76 | SRD5A1 (0.35) | OGA | |
| SCHEMBL15689459 | 0.75 | MAPT (0.46) | CHRNB2CHRNA4 | |
| SCHEMBL14720781 | 0.74 | HRH3 (0.45) | CHRNB2CHRNA4 | |
| SCHEMBL14720636 | 0.73 | CTH (0.33) | — | |
| SCHEMBL14721350 | 0.73 | HPGD (0.39) | OGA | |
| SCHEMBL17713023 | 0.73 | GRIN2D (0.44) | OGACHRNB2CHRNA4 | |
| SCHEMBL29108202 | 0.69 | CHRNB2 (0.32) | CHRNB2CHRNA4 | |
| SCHEMBL21550860 | 0.69 | TRPV6 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |