SCHEMBL14720950

SCHEMBL14720950

CCOC(=O)CN(Cc1cc(C#Cc2ccc(N)cc2)cc(CN(CC(=O)OCC)Cc2cc(-c3ccco3)cc(C(=O)OCC)n2)n1)Cc1cc(-c2ccco2)cc(C(=O)OCC)n1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.37
KDM4E B2RXH2 7/20 0.36
POLB P06746 6/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 8/20 0.35
HPGD P15428 4/20 0.35
HSD17B10 Q99714 3/20 0.35
ALOX15 P16050 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ADORA3 P0DMS8 3/20 0.35
ADORA2A P29274 3/20 0.35
ADORA1 P30542 3/20 0.35
ADORA2B P29275 2/20 0.35
ATM Q13315 1/20 0.34
TP53 P04637 1/20 0.34
PKM P14618 2/20 0.34
GAA P10253 1/20 0.33
USP2 O75604 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14720808 0.85 L3MBTL1 (0.41) L3MBTL1KDM4EPOLBMAPTALDH1A1
SCHEMBL14720914 0.84 KMT2A (0.39) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL14721258 0.83 ALDH1A1 (0.36) L3MBTL1KDM4EPOLBMAPTALDH1A1
SCHEMBL2367316 0.79 FFAR1 (0.35) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL2367405 0.76 PPIB (0.34) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL2108554 0.74 L3MBTL1 (0.51) L3MBTL1KDM4EPOLBMAPTALDH1A1
SCHEMBL3476583 0.73 L3MBTL1 (0.52) L3MBTL1KDM4EPOLBMAPTALDH1A1
SCHEMBL17595049 0.73 L3MBTL1 (0.59) L3MBTL1KDM4EPOLBMAPTALDH1A1
SCHEMBL14720800 0.69 MEN1 (0.35) POLBMAPTALDH1A1MEN1KMT2A
SCHEMBL19194844 0.69 L3MBTL1 (0.54) L3MBTL1KDM4EPOLBMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2753674-B1 LUMINESCENT LANTHANIDE CHELATES HAVING THREE CHROMOPHORES AND THEIR USE DHR FINLAND OY (FI) 2016-02-10 EP disclosed
US-20130210165-A1 Luminescent Lanthanide Chelates Having Three Chromophores and Their Use DHR FINLAND OY (FI) 2013-08-15 US disclosed
WO-2013026790-A9 LUMINESCENT LANTHANIDE CHELATES HAVING THREE CHROMOPHORES AND THEIR USE DHR FINLAND OY (FI) 2013-05-23 WO disclosed
WO-2013026790-A1 LUMINESCENT LANTHANIDE CHELATES HAVING THREE CHROMOPHORES AND THEIR USE DHR FINLAND OY (FI) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130210165-A1 Luminescent Lanthanide Chelates Having Three Chromophores and Their Use GLB1, SSB, LGALS3BP L3MBTL1 41/4885KDM4E 1897/4885POLB 3169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.