SCHEMBL14720914

SCHEMBL14720914

CCOC(=O)CN(Cc1cc(C#Cc2ccc(N)cc2)cc(CN(CC(=O)OCC)Cc2cc(-c3cccs3)cc(C(=O)OCC)n2)n1)Cc1cc(-c2cccs2)cc(C(=O)OCC)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.39
ALDH1A1 P00352 7/20 0.36
KDM4E B2RXH2 6/20 0.36
GAA P10253 5/20 0.36
MAPT P10636 4/20 0.36
KEAP1 Q14145 1/20 0.36
HDAC3 O15379 2/20 0.35
HDAC1 Q13547 2/20 0.35
HDAC2 Q92769 2/20 0.35
MEN1 O00255 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
TSHR P16473 2/20 0.35
RXFP1 Q9HBX9 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
LMNA P02545 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HPGD P15428 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14720912 0.85 KMT2A (0.44) KMT2AALDH1A1KDM4EGAAMAPT
SCHEMBL14720950 0.84 L3MBTL1 (0.37) KMT2AALDH1A1KDM4EGAAMAPT
SCHEMBL14721258 0.83 ALDH1A1 (0.36) KMT2AALDH1A1KDM4EGAAMAPT
SCHEMBL2367316 0.79 FFAR1 (0.35) KMT2AALDH1A1KDM4EGAAMAPT
SCHEMBL2367405 0.76 PPIB (0.34) KMT2AALDH1A1KDM4EGAAMAPT
SCHEMBL8209372 0.73 KMT2A (0.62) KMT2AALDH1A1KDM4EGAAMAPT
SCHEMBL14720800 0.69 MEN1 (0.35) KMT2AALDH1A1MAPTMEN1TSHR
SCHEMBL10367552 0.69 ACACB (0.37)
SCHEMBL14720808 0.67 L3MBTL1 (0.41) KMT2AALDH1A1KDM4EGAAMAPT
SCHEMBL5326532 0.67 APP (0.42) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2753674-B1 LUMINESCENT LANTHANIDE CHELATES HAVING THREE CHROMOPHORES AND THEIR USE DHR FINLAND OY (FI) 2016-02-10 EP disclosed
US-20130210165-A1 Luminescent Lanthanide Chelates Having Three Chromophores and Their Use DHR FINLAND OY (FI) 2013-08-15 US disclosed
WO-2013026790-A9 LUMINESCENT LANTHANIDE CHELATES HAVING THREE CHROMOPHORES AND THEIR USE DHR FINLAND OY (FI) 2013-05-23 WO disclosed
WO-2013026790-A1 LUMINESCENT LANTHANIDE CHELATES HAVING THREE CHROMOPHORES AND THEIR USE DHR FINLAND OY (FI) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130210165-A1 Luminescent Lanthanide Chelates Having Three Chromophores and Their Use GLB1, SSB, LGALS3BP KMT2A 4022/4885ALDH1A1 3095/4885KDM4E 1897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.