Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722402 | 0.93 | NPC1 (0.72) | TDP1NPC1RAB9ALMNACES2 | |
| SCHEMBL13410610 | 0.93 | TSHR (0.59) | TDP1NPC1RAB9ALMNAKMT2A | |
| P-Xylene SCHEMBL19206961 | 0.90 | LMNA (0.69) | TDP1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL6578044 | 0.89 | TDP1 (0.64) | TDP1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL416566 | 0.89 | TDP1 (0.91) | TDP1NPC1RAB9ALMNAKMT2A | |
| SCHEMBL14722604 | 0.87 | TSHR (0.54) | TDP1NPC1RAB9ALMNAKMT2A | |
| SCHEMBL14722275 | 0.87 | TSHR (0.54) | TDP1NPC1RAB9ALMNAKMT2A | |
| SCHEMBL6578053 | 0.87 | TDP1 (0.62) | TDP1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL14984030 | 0.87 | TDP1 (0.62) | TDP1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL28816330 | 0.87 | TDP1 (0.64) | TDP1NPC1RAB9ALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748246-A1 | 1,2-ALKYLENE-DI-P-TOLUATES AND -BENZOATES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE | Invista Technologies S.a r.l. (CH) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013026916-A1 | 1,2-ALKYLENE-DI-P-TOLUATES AND -BENZOATES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE | INVISTA TECHNOLOGIES S.À.R.L (CH) | 2013-02-28 | — | — | WO | disclosed |