SCHEMBL14722186

SCHEMBL14722186

O=C(c1ccccc1)c1ccc(SCCN(CCO)CCO)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
ALDH1A1 P00352 5/20 0.42
ACHE P22303 1/20 0.42
RAB9A P51151 5/20 0.42
NPC1 O15118 4/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
RECQL P46063 1/20 0.42
SRD5A2 P31213 1/20 0.42
HPGD P15428 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
NPY5R Q15761 1/20 0.40
HDAC1 Q13547 1/20 0.38
LMNA P02545 2/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11353930 0.85 HPGD (0.51) ALDH1A1ACHERAB9ANPC1SMN1; SMN2
SCHEMBL51274 0.84 GAA (0.54) GAAALDH1A1RAB9ANPC1SMN1; SMN2
Benzophenone SCHEMBL9545189 0.83 ALDH1A1 (0.61) GAAALDH1A1ACHERAB9ANPC1
SCHEMBL11306067 0.82 ALDH1A1 (0.58) GAAALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL11295147 0.81 HPGD (0.50) ALDH1A1RAB9ANPC1SMN1; SMN2RECQL
SCHEMBL11305194 0.76 GAA (0.50) GAAALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL16781459 0.76 KMT2A (0.54) GAAALDH1A1ACHERAB9ANPC1
SCHEMBL27233078 0.76 ACHE (0.51) GAAALDH1A1ACHERAB9ANPC1
SCHEMBL30655866 0.76 CA2 (0.53) GAAALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL15006838 0.76 HDAC1 (0.62) GAAALDH1A1RAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2638076-B1 NOVEL PHOTOINITIATORS COLOPLAST AS (DK) 2018-03-28 EP claimed
US-8946449-B2 Photoinitiators COLOPLAST A/S (DK) 2015-02-03 US claimed
EP-2638077-B1 NOVEL POLYMERIC PHOTOINITIATORS COLOPLAST AS (DK) 2015-01-07 EP claimed
EP-2638078-B1 NEW ROUTES TO POLYACRYLATES COLOPLAST AS (DK) 2015-01-07 EP claimed
EP-2744834-A1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES Lambson Limited (GB) 2014-06-25 EP claimed
US-20130296577-A1 NOVEL PHOTOINITIATORS COLOPLAST A/S (DK) 2013-11-07 US claimed
US-20130296454-A1 ROUTES TO POLYACRYLATES COLOPLAST A/S (DK) 2013-11-07 US claimed
US-20130289155-A1 NOVEL POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2013-10-31 US claimed
WO-2013026451-A1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES COLOPLAST A/S (DK) 2013-02-28 WO claimed
US-9670373-B2 Polymers comprising photoinitiator moieties and dye moieties LAMBSON LIMITED (GB) 2017-06-06 US disclosed
EP-2744834-B1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES LAMBSON LTD (GB) 2014-12-24 EP disclosed
US-20140316060-A1 Polymers Comprising Photoinitiator Moieties and Dye Moieties ARKEMA UK LIMITED (GB) 2014-10-23 US disclosed
EP-2744834-A1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES Lambson Limited (GB) 2014-06-25 EP disclosed
WO-2013026451-A1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES COLOPLAST A/S (DK) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130296577-A1 NOVEL PHOTOINITIATORS UROD, PUF60, PARG GAA 3256/4885ALDH1A1 536/4885ACHE 4282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.