Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HINT1 | P49773 | 3/20 | 0.41 |
| ▸ | TYMP | P19971 | 3/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441421 | 0.87 | TYMP (0.48) | TAS1R3TAS1R1TAAR1KDM4EHINT1 | |
| SCHEMBL441420 | 0.86 | TAS1R3 (0.44) | TAS1R3TAS1R1TAAR1KDM4EHINT1 | |
| SCHEMBL9294603 | 0.82 | TYMP (0.44) | TAS1R3TAS1R1TAAR1KDM4EHINT1 | |
| SCHEMBL5963306 | 0.82 | TYMP (0.44) | TAS1R3TAS1R1TAAR1KDM4EHINT1 | |
| SCHEMBL2115347 | 0.80 | TAS1R3 (0.54) | TAS1R3TAS1R1TAAR1HINT1TYMP | |
| SCHEMBL5963228 | 0.79 | TYMP (0.43) | TAS1R3TAS1R1TAAR1KDM4EHINT1 | |
| SCHEMBL18954966 | 0.78 | TYMP (0.68) | TAS1R3TAS1R1HINT1TYMPIMPDH2 | |
| SCHEMBL21160996 | 0.78 | TYMP (0.68) | TAS1R3TAS1R1HINT1TYMPIMPDH2 | |
| SCHEMBL21160998 | 0.78 | TYMP (0.68) | TAS1R3TAS1R1HINT1TYMPIMPDH2 | |
| SCHEMBL19493329 | 0.78 | TYMP (0.68) | TAS1R3TAS1R1HINT1TYMPIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609107-B1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) | 2024-12-11 | — | — | EP | disclosed |
| US-20210300954-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2021-09-30 | — | — | US | disclosed |
| US-11014948-B2 | Ionic tags for synthesis of oligoribonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2021-05-25 | — | — | US | disclosed |
| EP-2748176-B1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) | 2019-04-17 | — | — | EP | disclosed |
| US-9920084-B2 | Ionic tags for synthesis of oligoribonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2018-03-20 | — | — | US | disclosed |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2014-09-11 | — | — | US | disclosed |
| EP-2748176-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | The Royal Institution for the Advancement of Learning / McGill University (CA) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013026142-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11014948-B2 | Ionic tags for synthesis of oligoribonucleotides | RNGTT, OSTC, DTYMK | TAS1R3 3674/4885TAS1R1 3863/4885TAAR1 2383/4885 |
| US-20210300954-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | RNGTT, OSTC, DTYMK | TAS1R3 3674/4885TAS1R1 3863/4885TAAR1 2383/4885 |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | RNGTT, OSTC, OSGEP | TAS1R3 3715/4885TAS1R1 3894/4885TAAR1 2447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.