Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722836 | 0.97 | HRH3 (0.41) | HRH3L3MBTL3L3MBTL1MCHR1SRD5A2 | |
| SCHEMBL14720920 | 0.95 | HRH3 (0.47) | HRH3L3MBTL3L3MBTL1MCHR1SRD5A2 | |
| SCHEMBL14720608 | 0.92 | HRH3 (0.43) | HRH3L3MBTL3L3MBTL1MCHR1SRD5A2 | |
| SCHEMBL14720921 | 0.78 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1MCHR1CHRNA7HTR7 | |
| SCHEMBL14721035 | 0.78 | MCHR1 (0.36) | HRH3L3MBTL3L3MBTL1MCHR1SRD5A2 | |
| SCHEMBL14720311 | 0.78 | MCHR1 (0.38) | HRH3L3MBTL3L3MBTL1MCHR1SRD5A2 | |
| SCHEMBL14720913 | 0.77 | GPR183 (0.38) | HRH3L3MBTL3L3MBTL1MCHR1SRD5A2 | |
| SCHEMBL14721063 | 0.77 | HRH3 (0.47) | HRH3L3MBTL3L3MBTL1SRD5A2MBTD1 | |
| SCHEMBL14720496 | 0.77 | HRH3 (0.41) | HRH3L3MBTL3L3MBTL1SRD5A2SLC18A3 | |
| SCHEMBL14720838 | 0.77 | SRD5A2 (0.44) | HRH3L3MBTL3L3MBTL1SRD5A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |