Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25077473 | 0.88 | CYP19A1 (0.36) | CYP2C19CYP1A2CYP2C9CYP3A4S1PR3 | |
| SCHEMBL2526423 | 0.81 | CYP3A4 (0.41) | P2RX3P2RX2CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL20335430 | 0.81 | CYP1A2 (0.40) | P2RX3P2RX2CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL1842982 | 0.81 | KDM4E (0.51) | P2RX3P2RX2CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL5475832 | 0.81 | S1PR3 (0.45) | S1PR3CYP19A1ALDH1A1KDM4E | |
| SCHEMBL1841354 | 0.78 | P2RX3 (0.36) | P2RX3P2RX2CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL25077114 | 0.78 | CYP19A1 (0.42) | P2RX3P2RX2CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL25077116 | 0.78 | CYP19A1 (0.47) | P2RX3P2RX2CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL12536230 | 0.78 | KDM4E (0.40) | P2RX3P2RX2CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL1610377 | 0.78 | ALDH1A1 (0.54) | P2RX3P2RX2CYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140343049-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140343049-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140343049-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140235533-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-21 | — | — | US | disclosed |
| US-20140235533-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-21 | — | — | US | disclosed |
| US-20140235533-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-21 | — | — | US | disclosed |
| EP-2748137-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013026726-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013026724-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |
| US-7666979-B2 | polyvalent targeting ligands that bind to cells used for diagnosis of diseases sensitivity to angiogenesis factor | BRACCO INTERNATIONAL B.V. (NL) | 2010-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235533-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | DDT, CBR3, HRH4 | P2RX3 837/4885P2RX2 1189/4885CYP2C19 555/4885 |
| US-20140343049-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | NQO2, NIT2, QDPR | P2RX3 1056/4885P2RX2 790/4885CYP2C19 1768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.