Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13890689 | 0.85 | ALDH1A1 (0.35) | ALDH1A1MAPTPOLBMAPK1HSD17B10 | |
| SCHEMBL9877534 | 0.83 | SKP2 (0.42) | ALDH1A1MAPTPOLBTP53TSHR | |
| SCHEMBL881183 | 0.81 | ALDH1A1 (0.34) | ALDH1A1MAPTPOLBMAPK1HSD17B10 | |
| SCHEMBL13678595 | 0.77 | ALDH1A1 (0.35) | ALDH1A1MAPTMAPK1HSD17B10TP53 | |
| SCHEMBL17633458 | 0.76 | BCL2 (0.40) | — | |
| SCHEMBL10206836 | 0.75 | TDP1 (0.43) | ALDH1A1MAPTMAPK1HSD17B10TP53 | |
| SCHEMBL17633459 | 0.75 | — | — | |
| SCHEMBL7065478 | 0.74 | CYP3A4 (0.52) | ALDH1A1MAPTMAPK1HSD17B10TP53 | |
| SCHEMBL28289687 | 0.73 | MEN1 (0.59) | ALDH1A1MAPTPOLBMAPK1HSD17B10 | |
| SCHEMBL94119 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748311-A2 | GLUCOSE OXIDASE | Roche Diagniostics GmbH (DE) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013026575-A2 | GLUCOSE OXIDASE | ROCHE DIAGNOSTICS GMBH (DE) | 2013-02-28 | — | — | WO | disclosed |