Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MYLK | Q15746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722967 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL23009841 | 0.80 | PRKCE (0.35) | ALDH1A1PRKCEMAPTMYLKMEN1 | |
| SCHEMBL29713843 | 0.80 | PRKCE (0.35) | ALDH1A1PRKCEMAPTMYLKMEN1 | |
| SCHEMBL881190 | 0.79 | PRKCE (0.46) | ALDH1A1PRKCEMAPTMYLKMEN1 | |
| SCHEMBL9877534 | 0.77 | SKP2 (0.42) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL108757 | 0.75 | MAPT (0.44) | ALDH1A1PRKCEMAPTMYLKMEN1 | |
| SCHEMBL19899827 | 0.75 | MAPT (0.44) | ALDH1A1PRKCEMAPTMYLKMEN1 | |
| SCHEMBL10883526 | 0.75 | ALDH1A1 (0.48) | ALDH1A1PRKCEMAPTMYLKMEN1 | |
| SCHEMBL29354986 | 0.75 | MAPT (0.44) | ALDH1A1PRKCEMAPTMYLKMEN1 | |
| SCHEMBL13361211 | 0.75 | PRKCE (0.35) | ALDH1A1PRKCEMAPTMYLKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120078016-A1 | Methods of Synthesizing 2-Substituted-1,4-Benzenediamine | WELLA OPERATIONS US, LLC | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120078016-A1 | Methods of Synthesizing 2-Substituted-1,4-Benzenediamine | TYR, BTD, BRD4 | ALDH1A1 837/4885PRKCE 4848/4885MAPT 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.