Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795227 | 0.91 | SLC6A4 (0.44) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL27905533 | 0.89 | SLC6A2 (0.43) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL27905543 | 0.89 | SLC6A2 (0.43) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL5023299 | 0.89 | SLC6A2 (0.43) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL25306928 | 0.83 | SLC6A4 (0.49) | GABRA5GABRB2TSHRSLC6A4LMNA | |
| SCHEMBL4167603 | 0.83 | SLC6A4 (0.49) | GABRA5GABRB2TSHRSLC6A4LMNA | |
| SCHEMBL4594933 | 0.81 | SLC6A1 (0.35) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL296408 | 0.79 | GABRA1 (0.39) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| Hydrochloric Acid SCHEMBL3746410 | 0.77 | GABRA1 (0.38) | GABRA5GABRA1GABRB2TSHRGABRG2 | |
| SCHEMBL17699940 | 0.77 | SLC6A1 (0.47) | TSHRSLC6A4CPN1CPB2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |