Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905533 | 1.00 | SLC6A2 (0.43) | SLC6A2SLC6A4KCNH2CYP2D6SLC6A3 | |
| SCHEMBL27905543 | 1.00 | SLC6A2 (0.43) | SLC6A2SLC6A4KCNH2CYP2D6SLC6A3 | |
| SCHEMBL4167603 | 0.94 | SLC6A4 (0.49) | SLC6A2SLC6A4KCNH2CYP2D6SLC6A3 | |
| SCHEMBL25306928 | 0.94 | SLC6A4 (0.49) | SLC6A2SLC6A4KCNH2CYP2D6SLC6A3 | |
| SCHEMBL14723183 | 0.89 | GABRA5 (0.46) | SLC6A2SLC6A4KCNH2CYP2D6GABRA5 | |
| SCHEMBL17699940 | 0.88 | SLC6A1 (0.47) | SLC6A2SLC6A4KCNH2CYP2D6SLC6A3 | |
| SCHEMBL4594933 | 0.85 | SLC6A1 (0.35) | SLC6A2SLC6A4KCNH2CYP2D6SLC6A3 | |
| SCHEMBL27902620 | 0.83 | SLC6A2 (0.37) | SLC6A2SLC6A4KCNH2CYP2D6SLC6A3 | |
| SCHEMBL16795227 | 0.81 | SLC6A4 (0.44) | SLC6A2SLC6A4KCNH2CYP2D6SLC6A3 | |
| SCHEMBL1623816 | 0.81 | SLC6A4 (0.36) | SLC6A2SLC6A4KCNH2CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945606-A1 | ALKYLCARBAMOYL NAPHTHALENYLOXY- OCTENOYLHYDROXYAMIDE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007052938-A1 | ALKYLCARBAMOYL NAPHTHALENYLOXY- OCTENOYLHYDROXYAMIDE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-05-10 | — | — | WO | disclosed |