Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 7/20 | 0.43 |
| ▸ | TUBB | P07437 | 7/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14722160 | 0.99 | TUBB4A (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14721811 | 0.86 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14722512 | 0.86 | ALDH1A1 (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14721641 | 0.82 | CYP19A1 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Phenol SCHEMBL14723361 | 0.81 | TUBB4A (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14721668 | 0.81 | MAPT (0.37) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14721961 | 0.81 | CYP19A1 (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14722148 | 0.80 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14722260 | 0.79 | ALDH1A1 (0.34) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL14722766 | 0.79 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |