Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | FABP6 | P51161 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722320 | 0.87 | SRD5A1 (0.42) | SRD5A1FABP6SRD5A2MCHR1BRD4 | |
| SCHEMBL14722471 | 0.84 | SRD5A1 (0.42) | SRD5A1FABP6SRD5A2MCHR1HDAC2 | |
| SCHEMBL14721908 | 0.81 | HRH3 (0.36) | SRD5A2MCHR1IDH1 | |
| SCHEMBL14720416 | 0.79 | SRD5A1 (0.48) | SRD5A1SRD5A2MCHR1HDAC2OGA | |
| SCHEMBL14720576 | 0.72 | SRD5A1 (0.52) | SRD5A1SRD5A2MCHR1HDAC2OGA | |
| SCHEMBL14720707 | 0.72 | SRD5A1 (0.43) | SRD5A1SRD5A2MCHR1OGA | |
| SCHEMBL14720706 | 0.71 | SRD5A1 (0.51) | SRD5A1SRD5A2MCHR1HDAC2OGA | |
| SCHEMBL14722165 | 0.71 | SRD5A1 (0.51) | SRD5A1SRD5A2MCHR1HDAC2OGA | |
| SCHEMBL14722411 | 0.70 | SRD5A1 (0.44) | SRD5A1SRD5A2MCHR1HDAC2OGA | |
| SCHEMBL14731087 | 0.70 | KDM4E (0.42) | FABP6MCHR1BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |