Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14731087 | 0.84 | KDM4E (0.42) | HRH3MCHR1 | |
| SCHEMBL14723266 | 0.81 | SRD5A1 (0.40) | MCHR1SRD5A2IDH1 | |
| SCHEMBL14722538 | 0.80 | POLB (0.36) | HRH3SRD5A2L3MBTL3L3MBTL1POLB | |
| SCHEMBL14722283 | 0.77 | LMNA (0.41) | ACHE | |
| SCHEMBL14720643 | 0.76 | OPRM1 (0.41) | HRH3MCHR1L3MBTL3L3MBTL1 | |
| SCHEMBL14722373 | 0.75 | HRH3 (0.36) | HRH3CYP2D6SRD5A2 | |
| SCHEMBL14720575 | 0.75 | L3MBTL3 (0.51) | HRH3CYP2D6L3MBTL3L3MBTL1 | |
| SCHEMBL14721926 | 0.75 | POLB (0.39) | SRD5A2POLB | |
| SCHEMBL14720875 | 0.75 | FKBP1A (0.38) | HRH3SRD5A2POLB | |
| SCHEMBL14720876 | 0.75 | FKBP1A (0.38) | HRH3SRD5A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |