Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 2/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.34 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723605 | 0.85 | TP53 (0.46) | SRD5A1LMNASRD5A2POLBKMT2A | |
| SCHEMBL14720649 | 0.79 | FKBP1A (0.35) | LMNASRD5A2CYP2D6KMT2AALDH1A1 | |
| SCHEMBL14720576 | 0.76 | SRD5A1 (0.52) | SRD5A1SRD5A2MCHR1OGA | |
| SCHEMBL14720706 | 0.75 | SRD5A1 (0.51) | SRD5A1SRD5A2MCHR1OGA | |
| SCHEMBL14722165 | 0.75 | SRD5A1 (0.51) | SRD5A1SRD5A2MCHR1OGA | |
| SCHEMBL22683282 | 0.74 | SRD5A1 (0.50) | SRD5A1SRD5A2OGATDP1 | |
| SCHEMBL14720416 | 0.74 | SRD5A1 (0.48) | SRD5A1SRD5A2POLBMCHR1OGA | |
| SCHEMBL17750085 | 0.73 | LSS (0.51) | SRD5A1SRD5A2KMT2A | |
| SCHEMBL14722320 | 0.73 | SRD5A1 (0.42) | SRD5A1SRD5A2ALDH1A1MCHR1OGA | |
| SCHEMBL14722471 | 0.73 | SRD5A1 (0.42) | SRD5A1SRD5A2ALDH1A1MCHR1OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |