Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 12/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16155929 | 1.00 | DNM1 (0.37) | DNM1HTTPLA2G1BHSP90AA1RAD52 | |
| SCHEMBL14811054 | 0.98 | DNM1 (0.35) | DNM1HTTHSP90AA1RAD52LSS | |
| Hydrochloric Acid SCHEMBL10384670 | 0.76 | TSHR (0.38) | DNM1KMT2A | |
| Hydrochloric Acid SCHEMBL331220 | 0.76 | TSHR (0.38) | DNM1KMT2A | |
| Hydrochloric Acid SCHEMBL10383896 | 0.76 | TSHR (0.38) | DNM1KMT2A | |
| Hydrochloric Acid SCHEMBL1977629 | 0.76 | TSHR (0.38) | DNM1KMT2A | |
| SCHEMBL290064 | 0.74 | TSHR (0.36) | DNM1HTTKMT2A | |
| SCHEMBL15579564 | 0.74 | TSHR (0.36) | DNM1HTTKMT2A | |
| SCHEMBL1131620 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL6039649 | 0.74 | TSHR (0.37) | DNM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748431-A2 | FRACTURING PROCESS TO ENHANCE PROPPING AGENT DISTRIBUTION TO MAXIMIZE CONNECTIVITY BETWEEN THE FORMATION AND THE WELLBORE | Halliburton Energy Services, Inc. (US) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013028298-A2 | FRACTURING PROCESS TO ENHANCE PROPPING AGENT DISTRIBUTION TO MAXIMIZE CONNECTIVITY BETWEEN THE FORMATION AND THE WELLBORE | HALLIBURTON ENERGY SERVICES, INC. (US) | 2013-02-28 | — | — | WO | disclosed |