Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1977629 | 1.00 | TSHR (0.38) | TSHRDNM1TGFBR1SLC22A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10383896 | 1.00 | TSHR (0.38) | TSHRDNM1TGFBR1SLC22A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10384670 | 1.00 | TSHR (0.38) | TSHRDNM1TGFBR1SLC22A1ALDH1A1 | |
| SCHEMBL290064 | 0.98 | TSHR (0.36) | TSHRDNM1TGFBR1SLC22A1ALDH1A1 | |
| SCHEMBL15579564 | 0.98 | TSHR (0.36) | TSHRDNM1TGFBR1SLC22A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10425311 | 0.87 | TGFBR1 (0.39) | TGFBR1 | |
| Hydrochloric Acid SCHEMBL10384579 | 0.84 | TSHR (0.41) | TSHRTGFBR1PLA2G2APLA2G5 | |
| Hydrochloric Acid SCHEMBL10383887 | 0.84 | TSHR (0.41) | TSHRTGFBR1PLA2G2APLA2G5 | |
| SCHEMBL16224241 | 0.80 | TGFBR1 (0.36) | TGFBR1 | |
| Hydrochloric Acid SCHEMBL2489183 | 0.79 | ZDHHC20 (0.45) | TSHRDNM1SLC22A1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250374437-A1 | METHODS FOR PRODUCING AN ETCH RESIST PATTERN ON A METALLIC SURFACE | KATEEVA, INC. (US) | 2025-12-04 | — | — | US | claimed |
| CN-113597123-B | Method for producing etching-resistant pattern on metal surface and composition group thereof | 科迪华公司 | 2025-02-14 | — | — | CN | claimed |
| CN-113597123-A | Method for producing etch-resistant patterns on metal surfaces and composition set thereof | 科迪华公司 | 2021-11-02 | — | — | CN | claimed |
| CN-107710070-B | Method for producing etch-resistant patterns on metal surfaces and composition set thereof | 科迪华公司 | 2021-07-13 | — | — | CN | claimed |
| US-10610480-B2 | Personal care composition for a keratin substrate comprising conditioning, color protecting and styling polymer | ISP INVESTMENTS LLC (US) | 2020-04-07 | — | — | US | claimed |
| EP-3522859-A1 | PERSONAL CARE COMPOSITION FOR A KERATIN SUBSTRATE COMPRISING CONDITIONING, COLOR PROTECTING AND STYLING POLYMER | ISP Investments LLC (US) | 2019-08-14 | — | — | EP | claimed |
| US-20190099349-A1 | PERSONAL CARE COMPOSITION FOR A KERATIN SUBSTRATE COMPRISING CONDITIONING, COLOR PROTECTING AND STYLING POLYMER | ISP INVESTMENTS LLC (US) | 2019-04-04 | — | — | US | claimed |
| US-20180146556-A1 | METHODS FOR PRODUCING AN ETCH RESIST PATTERN ON A METALLIC SURFACE | JET CU PCB LTD. (IL) | 2018-05-24 | — | — | US | claimed |
| EP-3304197-A2 | METHODS FOR PRODUCING AN ETCH RESIST PATTERN ON A METALLIC SURFACE | Jet CU PCB Ltd. (IL) | 2018-04-11 | — | — | EP | claimed |
| WO-2018017570-A1 | A HAIR STRAIGHTENING AND STYLING COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC (US) | 2018-01-25 | — | — | WO | claimed |
| US-20080020004-A1 | Hair-Treatment Agent Comprising Terpolymer Of Vinylpyrrolidone, Methacrylamide And Vinylimidazole And Active Ingredients And Additives | WELLA AG (DE) | 2008-01-24 | — | — | US | claimed |
| US-20080019928-A1 | Clear, two-phase, foam-forming aerosol hairstyling product | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-24 | — | — | US | claimed |
| EP-1584323-B1 | Use of N-hydroxyalkyl-O-benzylchitosans in hair treatment | WELLA AG (DE) | 2007-10-24 | — | — | EP | claimed |
| US-20070244014-A1 | Filling formations with guar containing solutions; multimodal molecular weight distribution | HALLIBURTON ENERGY SERVICES, INC. | 2007-10-18 | — | — | US | claimed |
| EP-1809234-A1 | CLEAR, TOW-PHASE, FOAM-FORMING AEROSOL HAIRSTYLING PRODUCT | Wella Aktiengesellschaft (DE) | 2007-07-25 | — | — | EP | claimed |
| WO-2006050788-A1 | CLEAR, TWO-PHASE, FOAM-FORMING AEROSOL HAIRSTYLING PRODUCT | THE PROCTER & GAMBLE COMPANY (US) | 2006-05-18 | — | — | WO | claimed |
| US-20060013785-A1 | Hairstyling gels with light protective action for skin and hair | WELLA AG (DE) | 2006-01-19 | — | — | US | claimed |
| US-20050226838-A1 | Hair treatment compositions containing N-hydroxy-alkyl-O-benzyl chitosans and methods of using same | WELLA AG (DE) | 2005-10-13 | — | — | US | claimed |
| US-20050222001-A1 | Stable foamed compositions | WELLA AG (DE) | 2005-10-06 | — | — | US | claimed |
| US-4959432-A | HEAT RESISTANCE | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-09-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050226838-A1 | Hair treatment compositions containing N-hydroxy-alkyl-O-benzyl chitosans and methods of using same | CYP8B1, HAAO, TYR | TSHR 4502/4885DNM1 2998/4885TGFBR1 3736/4885 |
| US-20080020004-A1 | Hair-Treatment Agent Comprising Terpolymer Of Vinylpyrrolidone, Methacrylamide And Vinylimidazole And Active Ingredients And Additives | PLOD3, POLR1C, PTMA | TSHR 1689/4885DNM1 4873/4885TGFBR1 993/4885 |
| US-20060013785-A1 | Hairstyling gels with light protective action for skin and hair | SUCLG1, CUTA, MTCL3 | TSHR 3150/4885DNM1 4654/4885TGFBR1 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.