Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 4/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720779 | 0.82 | DDIT3 (0.34) | NAMPTSMN1; SMN2PIK3CAAKT1MTOR | |
| SCHEMBL14720896 | 0.75 | GRM5 (0.46) | GPR119RECQLUSP2SMN1; SMN2 | |
| SCHEMBL1870570 | 0.75 | NR1H2 (0.54) | GPR119USP2SMN1; SMN2 | |
| SCHEMBL4635083 | 0.75 | GRM5 (0.46) | GPR119USP2SMN1; SMN2 | |
| SCHEMBL5497099 | 0.75 | MEN1 (0.55) | USP2SMN1; SMN2STS | |
| SCHEMBL14720486 | 0.75 | NAMPT (0.38) | NAMPTSMN1; SMN2 | |
| SCHEMBL1473227 | 0.75 | GPR119 (0.51) | GPR119STS | |
| SCHEMBL23546383 | 0.74 | GPR119 (0.60) | GPR119NAMPTSTS | |
| SCHEMBL4768567 | 0.74 | GPR119 (0.68) | GPR119NAMPT | |
| SCHEMBL20304919 | 0.74 | SRD5A2 (0.55) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |