Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDIT3 | P35638 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 4/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723487 | 0.82 | GPR119 (0.45) | NAMPTPIK3CAAKT1MTORSMN1; SMN2 | |
| SCHEMBL14720486 | 0.81 | NAMPT (0.38) | MEN1NAMPTSRD5A2ALDH1A1KMT2A | |
| SCHEMBL14720851 | 0.79 | HTR2C (0.39) | DDIT3MEN1NAMPTGCKTXNRD1 | |
| SCHEMBL14720435 | 0.69 | MCHR1 (0.37) | SRD5A2MAPTKMT2A | |
| SCHEMBL17713023 | 0.68 | GRIN2D (0.44) | SRD5A2OGAALDH1A1MAPTHTT | |
| SCHEMBL5319901 | 0.68 | MMP13 (0.45) | DDIT3TXNRD1ALDH1A1MAPT | |
| SCHEMBL17008693 | 0.68 | HTR2A (0.50) | — | |
| SCHEMBL6120462 | 0.68 | HTR2A (0.40) | MEN1ALDH1A1KMT2A | |
| SCHEMBL15232568 | 0.68 | HTR2A (0.40) | ALDH1A1HTT | |
| SCHEMBL15689389 | 0.67 | CHRNA7 (0.44) | OGAALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |