Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | OGA | O60502 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723483 | 0.83 | L3MBTL3 (0.55) | HRH3L3MBTL3L3MBTL1KCNH2 | |
| SCHEMBL14720398 | 0.78 | HRH3 (0.45) | HRH3OGAKCNH2 | |
| SCHEMBL14720751 | 0.77 | HRH3 (0.52) | HRH3OGAMAPK1L3MBTL1 | |
| SCHEMBL14731083 | 0.77 | SRD5A2 (0.46) | HRH3 | |
| SCHEMBL14721178 | 0.76 | HRH3 (0.43) | HRH3 | |
| SCHEMBL14720781 | 0.75 | HRH3 (0.45) | HRH3 | |
| SCHEMBL14720551 | 0.74 | ALDH1A1 (0.56) | MAPK1 | |
| SCHEMBL29108250 | 0.74 | MAPK1 (0.50) | OGAMAPK1L3MBTL1 | |
| SCHEMBL14720329 | 0.73 | HRH3 (0.35) | HRH3KCNH2 | |
| SCHEMBL14731087 | 0.72 | KDM4E (0.42) | HRH3OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |