Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000101 | 0.85 | PSMD14 (0.39) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL3017476 | 0.83 | ADRA2A (0.47) | MAPTMEN1KMT2ATP53SLC6A2 | |
| SCHEMBL13247044 | 0.80 | MAPT (0.45) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL13247043 | 0.79 | CFTR (0.43) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9864313 | 0.77 | PSMD14 (0.42) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL16060314 | 0.75 | SLC6A3 (0.65) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL13247008 | 0.71 | ADRA2A (0.49) | MAPTLMNASMN1; SMN2TDP1TP53 | |
| SCHEMBL13247003 | 0.71 | ADRA2A (0.43) | MAPTLMNASMN1; SMN2TDP1TP53 | |
| SCHEMBL701285 | 0.69 | ADRA2A (0.47) | TP53PSMD14COPS5SLC6A2SLC6A4 | |
| SCHEMBL13247020 | 0.69 | CYP1A2 (0.40) | MAPTLMNASMN1; SMN2TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383646-B2 | Therapeutic ((bicylicheteroaryl)imidazolyl) methylheteroaryl compounds | ALLERGAN, INC. (US) | 2013-02-26 | — | — | US | disclosed |