Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28807672 | 0.86 | DPP4 (0.35) | TDP1GABRA1GABRG2GABRB3TSHR | |
| SCHEMBL6055136 | 0.85 | GABRA1 (0.48) | TDP1GABRA1GABRG2GABRB3TSHR | |
| SCHEMBL30606846 | 0.85 | GABRA1 (0.48) | TDP1GABRA1GABRG2GABRB3TSHR | |
| Hydrochloric Acid SCHEMBL25189937 | 0.83 | GABRA1 (0.47) | TDP1GABRA1GABRG2GABRB3TSHR | |
| SCHEMBL872725 | 0.83 | ADRA2A (0.44) | GABRA1TSHRGABRB2CYSLTR2CYSLTR1 | |
| SCHEMBL1561218 | 0.83 | GABRA1 (0.45) | GABRA1GABRG2GABRB3TSHRGABRB2 | |
| SCHEMBL29142040 | 0.82 | PTGS2 (0.35) | GABRA1GABRG2GABRB3TSHRADRB2 | |
| SCHEMBL11688468 | 0.82 | TDP1 (0.37) | TDP1GABRA1GABRG2GABRB3TSHR | |
| SCHEMBL28947479 | 0.82 | TAAR1 (0.50) | TSHRSLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL27358739 | 0.82 | TSHR (0.35) | GABRA1GABRG2GABRB3TSHRGABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562162-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-2562166-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-2562175-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |