Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959700 | 0.85 | TSHR (0.50) | TSHRSMN1; SMN2GPBAR1CYSLTR1CYP4F2 | |
| SCHEMBL9859582 | 0.85 | TSHR (0.50) | TSHRSMN1; SMN2GPBAR1CYSLTR1CYP4F2 | |
| SCHEMBL16902891 | 0.83 | TSHR (0.56) | TSHRSMN1; SMN2GPBAR1CYSLTR1CYP4F2 | |
| SCHEMBL13239972 | 0.83 | BCHE (0.42) | TSHRSMN1; SMN2CYP4F2CYP4A11TTR | |
| SCHEMBL10602833 | 0.82 | TSHR (0.54) | TSHRSMN1; SMN2GPBAR1CYSLTR1CYP4F2 | |
| SCHEMBL16902876 | 0.82 | TSHR (0.54) | TSHRSMN1; SMN2GPBAR1CYSLTR1CYP4F2 | |
| SCHEMBL320330 | 0.80 | HIF1A (0.45) | TSHRSMN1; SMN2MAOB | |
| SCHEMBL14724394 | 0.80 | ALDH1A1 (0.57) | TSHRSMN1; SMN2GPBAR1CYSLTR1CYP4F2 | |
| SCHEMBL16902882 | 0.80 | TSHR (0.53) | TSHRSMN1; SMN2GPBAR1CYSLTR1CYP4F2 | |
| SCHEMBL126287 | 0.80 | TP53 (0.55) | TSHRSMN1; SMN2GPBAR1CYSLTR1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562175-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |