Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13529972 | 0.88 | KMT2A (0.43) | KMT2AMAPK1RAB9APKMALDH1A1 | |
| SCHEMBL13529782 | 0.88 | KMT2A (0.53) | KMT2AMAPK1RAB9APKMALDH1A1 | |
| SCHEMBL13529914 | 0.87 | KMT2A (0.43) | KMT2AMAPK1RAB9APKMALDH1A1 | |
| SCHEMBL13530116 | 0.85 | MAPK1 (0.44) | KMT2AMAPK1RAB9APKMALDH1A1 | |
| SCHEMBL13529473 | 0.85 | HPGD (0.51) | KMT2AMAPK1RAB9APKMALDH1A1 | |
| SCHEMBL13529438 | 0.83 | ROCK2 (0.46) | KMT2AMAPK1RAB9APKMROCK2 | |
| SCHEMBL13529391 | 0.82 | LMNA (0.41) | KMT2AMAPK1RAB9APKMALDH1A1 | |
| SCHEMBL13529692 | 0.82 | RAB9A (0.58) | KMT2AMAPK1RAB9APKMALDH1A1 | |
| SCHEMBL13530094 | 0.82 | KMT2A (0.53) | KMT2AMAPK1RAB9APKMALDH1A1 | |
| SCHEMBL13765106 | 0.81 | ROCK2 (0.44) | KMT2AMAPK1RAB9APKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562175-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |