SCHEMBL14725296

SCHEMBL14725296

c1ccc2c(c1)sc1c(-c3cc(-c4cc(-c5cc(-c6cccc7c6sc6ccccc67)cc(-c6cccc7c6sc6ccccc67)c5)ncn4)cc(-c4cccc5c4sc4ccccc45)c3)cccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.54
LIMK1 P53667 5/20 0.42
CDK5 Q00535 1/20 0.41
CDK5R1 Q15078 1/20 0.41
PARP14 Q460N5 1/20 0.41
PRKDC P78527 4/20 0.40
DNPH1 O43598 1/20 0.39
ADK P55263 1/20 0.39
HTT P42858 1/20 0.38
PAX8 Q06710 1/20 0.38
GPR3 P46089 1/20 0.37
EGFR P00533 1/20 0.37
MAPT P10636 1/20 0.37
HTR2C P28335 1/20 0.36
HRH4 Q9H3N8 1/20 0.36
PIK3CA P42336 2/20 0.36
PIK3CD O00329 2/20 0.36
PIK3CB P42338 2/20 0.36
BRD4 O60885 1/20 0.36
MTOR P42345 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14725290 0.95 ALOX5 (0.49) ALOX5LIMK1CDK5CDK5R1PARP14
SCHEMBL29362957 0.93 ALOX5 (0.56) ALOX5LIMK1CDK5CDK5R1PARP14
SCHEMBL14718150 0.93 ALOX5 (0.56) ALOX5LIMK1CDK5CDK5R1PARP14
SCHEMBL14725283 0.92 ALOX5 (0.55) ALOX5LIMK1CDK5CDK5R1PARP14
SCHEMBL14725284 0.89 ALOX5 (0.52) ALOX5LIMK1CDK5CDK5R1PARP14
SCHEMBL22376167 0.89 ALOX5 (0.46) ALOX5LIMK1CDK5CDK5R1PARP14
SCHEMBL15455771 0.89 ALOX5 (0.52) ALOX5LIMK1CDK5CDK5R1PARP14
SCHEMBL14725287 0.87 ALOX5 (0.50) ALOX5LIMK1CDK5CDK5R1PARP14
SCHEMBL17345751 0.87 ALOX5 (0.49) ALOX5LIMK1CDK5CDK5R1PARP14
SCHEMBL29450673 0.86 ALOX5 (0.68) ALOX5LIMK1PARP14PRKDCGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026217-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-01-25 US disclosed
US-20240026217-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-01-25 US disclosed
US-11773321-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-03 US disclosed
US-11773321-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-03 US disclosed
US-20210277305-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-09-09 US disclosed
US-11008510-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-05-18 US disclosed
US-20170253796-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-09-07 US disclosed
US-20170253796-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-09-07 US disclosed
US-9663711-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-30 US disclosed
US-9663711-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-30 US disclosed
US-20130048964-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2013-02-28 US disclosed
US-20130048964-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2013-02-28 US disclosed
WO-2013027846-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, LIGHTING DEVICE, AND NOVEL ORGANIC COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048964-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound LAGE3, LEF1, PUM2 ALOX5 112/4885LIMK1 18/4885CDK5 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.