Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 6/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.34 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.34 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.34 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.34 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.34 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.34 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.34 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.34 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.34 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.34 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.34 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.34 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.34 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.34 |
| ▸ | PSMA8 | Q8TAA3 | 2/20 | 0.34 |
| ▸ | PSMB7 | Q99436 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721273 | 0.93 | METAP2 (0.40) | PSMB5AAK1IL1RNERAP2ERAP1 | |
| SCHEMBL14721499 | 0.89 | PSEN1 (0.40) | REN | |
| SCHEMBL14725252 | 0.88 | METAP2 (0.38) | PSMB5BIRC2IL1RNERAP2ERAP1 | |
| Carbamic Acid SCHEMBL14722093 | 0.82 | SRC (0.39) | CTSKRENCTSLCTSSAAK1 | |
| SCHEMBL14725258 | 0.82 | METAP2 (0.40) | PSMB5AAK1IL1RNERAP2ERAP1 | |
| SCHEMBL14721711 | 0.79 | GSK3B (0.36) | AAK1ALDH1A1 | |
| SCHEMBL14725494 | 0.78 | PSEN1 (0.42) | REN | |
| SCHEMBL14722096 | 0.77 | SRC (0.37) | RENAAK1ALDH1A1 | |
| SCHEMBL14722027 | 0.73 | TSHR (0.43) | CTSKRENCTSLCTSSAAK1 | |
| SCHEMBL14725254 | 0.72 | METAP2 (0.42) | PSMB5AAK1ALDH1A1ALOX15IL1RN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |