Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29378202 | 0.92 | TSHR (0.45) | HDAC6ALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL218327 | 0.92 | TSHR (0.45) | HDAC6ALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL20323198 | 0.87 | HDAC6 (0.46) | HDAC6ALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL16281992 | 0.84 | TSHR (0.44) | HDAC6ALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL9767684 | 0.83 | ALDH1A1 (0.50) | HDAC6ALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL3651606 | 0.82 | HTT (0.43) | HDAC6ALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL27994148 | 0.82 | HTT (0.43) | HDAC6ALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL9958252 | 0.82 | TSHR (0.49) | ALDH1A1TSHRMAPK1LMNAL3MBTL1 | |
| SCHEMBL15865271 | 0.81 | TDP1 (0.56) | HDAC6ALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL2706082 | 0.81 | ALDH1A1 (0.47) | HDAC6ALDH1A1TSHRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732257-B2 | Curable acrylate or methacrylate compositions | Henkel IP & Holding GmbH (DE) | 2017-08-15 | — | — | US | disclosed |
| US-9212244-B2 | Polymers made from mixtures comprising vinyl ether monomers | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2015-12-15 | — | — | US | disclosed |
| US-8580888-B2 | Two-part, cyanoacrylate/cationically curable adhesive systems | HENKEL IRELAND LIMITED (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20130053497-A1 | TWO-PART, CYANOACRYLATE/CATIONICALLY CURABLE ADHESIVE SYSTEMS | HENKEL IRELAND LTD. (IE) | 2013-02-28 | — | — | US | disclosed |