Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 12/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL325802 | 0.96 | TTK (0.34) | TTKNPC1RAB9AUSP30HPGD | |
| SCHEMBL19063431 | 0.88 | TTK (0.34) | TTKNPC1RAB9AUSP30HPGD | |
| SCHEMBL1806620 | 0.88 | TTK (0.34) | TTKNPC1RAB9AUSP30HPGD | |
| SCHEMBL14961949 | 0.85 | NPC1 (0.34) | TTKNPC1RAB9AUSP30HPGD | |
| SCHEMBL15239866 | 0.85 | SMN1; SMN2 (0.35) | TTKUSP30CRHR1 | |
| SCHEMBL14855742 | 0.85 | SMN1; SMN2 (0.35) | TTKUSP30CRHR1 | |
| SCHEMBL3665360 | 0.85 | SMN1; SMN2 (0.35) | TTKUSP30CRHR1 | |
| SCHEMBL1806024 | 0.85 | RXRA (0.38) | TTKUSP30CRHR1 | |
| SCHEMBL20336183 | 0.84 | — | — | |
| SCHEMBL12173977 | 0.84 | TTK (0.33) | TTKUSP30CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026929-A1 | DIHYDROPYRROLE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |