Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 12/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14726009 | 0.96 | TTK (0.34) | TTKNPC1RAB9AUSP30HPGD | |
| SCHEMBL1806620 | 0.92 | TTK (0.34) | TTKNPC1RAB9AUSP30HPGD | |
| SCHEMBL19063431 | 0.92 | TTK (0.34) | TTKNPC1RAB9AUSP30HPGD | |
| SCHEMBL14855742 | 0.90 | SMN1; SMN2 (0.35) | TTKUSP30CRHR1 | |
| SCHEMBL3665360 | 0.90 | SMN1; SMN2 (0.35) | TTKUSP30CRHR1 | |
| SCHEMBL15239866 | 0.90 | SMN1; SMN2 (0.35) | TTKUSP30CRHR1 | |
| SCHEMBL1806024 | 0.89 | RXRA (0.38) | TTKUSP30CRHR1 | |
| SCHEMBL12173977 | 0.89 | TTK (0.33) | TTKUSP30CRHR1 | |
| SCHEMBL20336183 | 0.89 | — | — | |
| SCHEMBL20336147 | 0.88 | CNR2 (0.34) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364235-B2 | Insecticidal compounds | Synenta Crop Protection LLC (US) | 2019-07-30 | — | — | US | disclosed |
| US-10364235-B2 | Insecticidal compounds | Synenta Crop Protection LLC (US) | 2019-07-30 | — | — | US | disclosed |
| US-20180065956-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2018-03-08 | — | — | US | disclosed |
| US-20180065956-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2018-03-08 | — | — | US | disclosed |
| US-9834546-B2 | Insecticidal compounds | SYNGENTA LIMITED (GB) | 2017-12-05 | — | — | US | disclosed |
| US-9834546-B2 | Insecticidal compounds | SYNGENTA LIMITED (GB) | 2017-12-05 | — | — | US | disclosed |
| US-20170022187-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2017-01-26 | — | — | US | disclosed |
| US-20170022187-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2017-01-26 | — | — | US | disclosed |
| US-9493445-B2 | Insecticidal compounds | SYNGENTA LIMITED (GB) | 2016-11-15 | — | — | US | disclosed |
| US-9493445-B2 | Insecticidal compounds | SYNGENTA LIMITED (GB) | 2016-11-15 | — | — | US | disclosed |
| US-20130131137-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-05-23 | — | — | US | disclosed |
| EP-2445906-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2012-05-02 | — | — | EP | disclosed |
| WO-2012049327-A2 | PESTICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-04-19 | — | — | WO | disclosed |
| US-8158560-B2 | Insecticidal arylpyrroline compounds | BAYER CROPSCIENCE AG (DE) | 2012-04-17 | — | — | US | disclosed |
| WO-2012004326-A1 | PESTICIDAL PYRROLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | WO | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| WO-2010149506-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149506-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010020522-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022187-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | TTK 4789/4885NPC1 319/4885RAB9A 193/4885 |
| US-20130131137-A1 | INSECTICIDAL COMPOUNDS | F5, CHRM1, CHRM2 | TTK 3823/4885NPC1 995/4885RAB9A 116/4885 |
| US-10364235-B2 | Insecticidal compounds | ACHE, CHRM1, NIT2 | TTK 4789/4885NPC1 319/4885RAB9A 193/4885 |
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | DDT, LAP3, CYP4X1 | TTK 4822/4885NPC1 4027/4885RAB9A 797/4885 |
| US-20180065956-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | TTK 4789/4885NPC1 319/4885RAB9A 193/4885 |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, C1R | TTK 4641/4885NPC1 562/4885RAB9A 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.