Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 12/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14855742 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2GLATTKDGAT2USP30 | |
| SCHEMBL15239866 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2GLATTKDGAT2USP30 | |
| SCHEMBL1802941 | 0.92 | RORC (0.34) | SMN1; SMN2GLATTKUSP30CRHR1 | |
| SCHEMBL1806466 | 0.90 | RXRA (0.37) | SMN1; SMN2GLATTKUSP30CRHR1 | |
| SCHEMBL325802 | 0.90 | TTK (0.34) | TTKUSP30CRHR1 | |
| SCHEMBL20336152 | 0.87 | CNR2 (0.34) | — | |
| SCHEMBL12173977 | 0.87 | TTK (0.33) | TTKUSP30CRHR1 | |
| SCHEMBL16888714 | 0.86 | DGAT2 (0.34) | TTKDGAT2 | |
| SCHEMBL14641808 | 0.86 | EGLN1 (0.38) | TTK | |
| SCHEMBL1802939 | 0.85 | TTK (0.33) | TTKUSP30CRHR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216973-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| US-20150189883-A1 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-09 | — | — | US | disclosed |
| EP-2331536-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-08-21 | — | — | EP | disclosed |
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-27 | — | — | US | disclosed |
| WO-2012049327-A2 | PESTICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-04-19 | — | — | WO | disclosed |
| US-8158560-B2 | Insecticidal arylpyrroline compounds | BAYER CROPSCIENCE AG (DE) | 2012-04-17 | — | — | US | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| WO-2011054871-A1 | INSECTICIDAL ARYLPYRROLINE COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2011-05-12 | — | — | WO | disclosed |
| WO-2010020522-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150189883-A1 | METHODS OF CONTROLLING INSECTS | CRY1, CYCS, CCNB1 | SMN1; SMN2 4708/4885GLA 3389/4885TTK 3649/4885 |
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, CHRM5 | SMN1; SMN2 585/4885GLA 2113/4885TTK 4533/4885 |
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | DDT, LAP3, CYP4X1 | SMN1; SMN2 1442/4885GLA 3105/4885TTK 4822/4885 |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, C1R | SMN1; SMN2 579/4885GLA 2476/4885TTK 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.