Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.79 |
| ▸ | CA2 | P00918 | 3/20 | 0.79 |
| ▸ | CA12 | O43570 | 2/20 | 0.79 |
| ▸ | CA9 | Q16790 | 2/20 | 0.79 |
| ▸ | CA5A | P35218 | 1/20 | 0.79 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 8/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | HTT | P42858 | 5/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | DDX3X | O00571 | 2/20 | 0.71 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | BAZ1A | Q9NRL2 | 3/20 | 0.63 |
| ▸ | IDH1 | O75874 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL672979 | 0.88 | CA2 (1.00) | CA1CA2CA12CA9CA5A | |
| SCHEMBL1047211 | 0.84 | MEN1 (1.00) | CA1CA2CA12CA9CA5A | |
| SCHEMBL12111855 | 0.84 | CA12 (0.70) | CA1CA2CA12CA9CA5A | |
| SCHEMBL1311061 | 0.83 | MEN1 (0.79) | CA1CA2CA12CA9CA5A | |
| SCHEMBL6129390 | 0.83 | MEN1 (0.90) | CA1CA2CA12CA9CA5A | |
| SCHEMBL17084065 | 0.83 | MEN1 (0.96) | CA1CA2CA12CA9CA5A | |
| SCHEMBL673171 | 0.83 | CA2 (1.00) | CA1CA2CA12CA9CA5A | |
| Ammonia Solution, Strong SCHEMBL20268307 | 0.82 | MEN1 (0.77) | CA1CA2CA12CA9CA5A | |
| SCHEMBL12112907 | 0.82 | CA12 (0.67) | CA1CA2CA12CA9CA5A | |
| SCHEMBL22092552 | 0.81 | MEN1 (0.79) | CA1CA2CA12CA9CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | UNIVERSITETET I OSLO (NO) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | CA9, CA2, CA4 | CA1 5/4885CA2 2/4885CA12 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.