SCHEMBL147268

SCHEMBL147268

C=C(C)C(=O)OCC(COC(=O)C(=C)C)COC(=O)C(=C)C

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.71
THRB P10828 1/20 0.48
ALDH1A1 P00352 4/20 0.46
TDP1 Q9NUW8 5/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 2/20 0.31
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3685216 0.89 TSHR (0.63) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL3974700 0.89 TSHR (0.63) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL65970 0.89 TSHR (0.63) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL75001 0.89 TSHR (0.63) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL22141761 0.87 TSHR (0.61) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL12752227 0.86 TSHR (0.55) TSHRTHRBALDH1A1HSD17B10CYP3A4
SCHEMBL497290 0.85 TSHR (0.59) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL8956027 0.85 TSHR (0.59) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL6757327 0.85 TSHR (0.59) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL17201703 0.85 TSHR (0.59) TSHRTHRBALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192477-A Organic silicon sulfonate with low-temperature toughening and flame retardance functions, and preparation method and application thereof 铨盛聚碳科技股份有限公司 2025-06-24 CN claimed
CN-111050903-B Chromatographic packing material for separating and/or detecting methylated DNA 积水医疗株式会社 2023-02-28 CN claimed
CN-106866971-B Weather-resistant low-temperature-resistant organic silicon impact modifier and preparation method and application thereof 广东优科艾迪高分子材料有限公司 2020-05-05 CN claimed
CN-111050903-A Chromatographic packing material for separating and/or detecting methylated DNA 积水医疗株式会社 2020-04-21 CN claimed
US-9763753-B2 Method of dental implant restoration ZUGA MEDICAL, INC. (US) 2017-09-19 US claimed
US-9566216-B2 Bone cements containing magnetic calcium phosphate nanoparticles SOUTHWEST RESEARCH INSTITUTE (US) 2017-02-14 US claimed
US-20150142112-A1 Bone Cements Containing Magnetic Calcium Phosphate Nanoparticles SOUTHWEST RESEARCH INSTITUTE 2015-05-21 US claimed
US-20140302459-A1 Method of dental implant restoration SICHUAN PROVINCE HEALTH PENSION INDUSTRY EQUITY INVESTMENT FUND LIMITED PARTNERSHIP 2014-10-09 US claimed
US-20100099058-A1 Method of Dental Implant Restoration SICHUAN PROVINCE HEALTH PENSION INDUSTRY EQUITY INVESTMENT FUND LIMITED PARTNERSHIP 2010-04-22 US claimed
US-7259210-B2 Bone cement and a system for mixing and delivery thereof THE UAB RESEARCH FOUNDATION (US) 2007-08-21 US claimed
EP-1367960-B1 BONE CEMENT UAB RESEARCH FOUNDATION (US) 2005-11-02 EP claimed
US-20040132859-A1 Bone cement and a system for mixing and delivery thereof PUCKETT JR AARON D (US) 2004-07-08 US claimed
EP-1367960-A4 BONE CEMENT AND A SYSTEM FOR MIXING AND DELIVERY THEREOF UAB RESEARCH FOUNDATION (US) 2004-06-09 EP claimed
EP-1367960-A2 BONE CEMENT AND A SYSTEM FOR MIXING AND DELIVERY THEREOF UAB Research Foundation (US) 2003-12-10 EP claimed
WO-2002058592-A9 BONE CEMENT AND A SYSTEM FOR MIXING AND DELIVERY THEREOF UAB RESEARCH FOUNDATION (US) 2003-11-27 WO claimed
US-6506815-B2 Does not require operations for weighing, and mixing during during use; free from involving of air bubbles; denture has high elastic energy value, is superior in impact resistance GC CORPORATION (JP) 2003-01-14 US claimed
WO-2002058592-A2 BONE CEMENT AND A SYSTEM FOR MIXING AND DELIVERY THEREOF UAB RESEARCH FOUNDATION (US) 2002-08-01 WO claimed
US-5364890-A (meth)acrylate and a carbodiimide GC CORPORATION (JP) 1994-11-15 US claimed
CN-120192477-A Organic silicon sulfonate with low-temperature toughening and flame retardance functions, and preparation method and application thereof 铨盛聚碳科技股份有限公司 2025-06-24 CN disclosed
US-4820744-A TWO PARTS-UNSATURATED COMPOUND, INITIATOR, AND REDUCING AGENT SEPARATED FROM ORGANIC PEROXIDE AND FILLER G-C DENTAL INDUSTRIAL CORP. (JP) 1989-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150142112-A1 Bone Cements Containing Magnetic Calcium Phosphate Nanoparticles ACP1, ACP3, BMP2 TSHR 4854/4885THRB 3899/4885ALDH1A1 3912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.