Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685216 | 0.96 | TSHR (0.63) | TSHRTHRBALDH1A1TGFBR1POLB | |
| SCHEMBL481538 | 0.90 | TSHR (0.57) | TSHRTHRBALDH1A1TGFBR1POLB | |
| SCHEMBL147268 | 0.89 | TSHR (0.71) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL5879358 | 0.87 | TSHR (0.53) | TSHRTHRBALDH1A1TDP1 | |
| SCHEMBL274524 | 0.87 | TSHR (0.53) | TSHRTHRBALDH1A1TGFBR1 | |
| SCHEMBL2442706 | 0.85 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1 | |
| SCHEMBL886786 | 0.85 | TSHR (0.52) | TSHRTHRBALDH1A1 | |
| SCHEMBL884873 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1 | |
| SCHEMBL75001 | 0.83 | TSHR (0.63) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL3974700 | 0.83 | TSHR (0.63) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 641 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3482740-B1 | DENTAL PHOTOPOLYMERIZABLE COMPOSITION | G C DENTAL IND CORP (JP) | 2024-03-27 | — | — | EP | claimed |
| EP-2527372-B1 | Waterborne, radiation-curable coating compositions and related methods | PPG IND OHIO INC (US) | 2021-05-26 | — | — | EP | claimed |
| EP-2091976-B1 | WATERBORNE, RADIATION-CURABLE COATING COMPOSITIONS AND RELATED METHODS | PPG IND OHIO INC (US) | 2021-05-05 | — | — | EP | claimed |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2021-02-25 | — | — | US | claimed |
| EP-2623087-B1 | Dental composite materials containing tricyclic plasticisers | VOCO GMBH (DE) | 2019-07-17 | — | — | EP | claimed |
| EP-2623086-B1 | Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. | VOCO GMBH (DE) | 2019-07-10 | — | — | EP | claimed |
| US-9925124-B2 | Dental composition suitable for grinding with automatic grinding apparatus | KABUSHIKI KAISHA SHOFU (JP) | 2018-03-27 | — | — | US | claimed |
| US-9079994-B2 | Polymerizable compositions | GC CORPORATION (JP) | 2015-07-14 | — | — | US | claimed |
| US-20130203884-A1 | DENTAL COMPOSITE MATERIALS COMPRISING TRICYCLIC PLASTICIZERS | VOCO GMBH (DE) | 2013-08-08 | — | — | US | claimed |
| US-8367745-B2 | Includes alkaline earth metal oxide as acidity neutralization stabilizer; quick setting, mechanical strength; repairing prosthesis | GC CORPORATION (JP) | 2013-02-05 | — | — | US | claimed |
| US-8247470-B2 | Polymerizable composition | GC CORPORATION (JP) | 2012-08-21 | — | — | US | claimed |
| US-20090018234-A1 | DENTAL CEMENT | GC CORPORATION (JP) | 2009-01-15 | — | — | US | claimed |
| US-4921930-A | ABRASION RESISTANT POLYESTERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-01 | — | — | US | claimed |
| US-4910281-A | Polyurethane from diol and diisocyanate | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-03-20 | — | — | US | claimed |
| EP-0309249-A2 | Acryloyloxy and methacryloyloxy group-containing condensation polymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-03-29 | — | — | EP | claimed |
| JP-63027554-A | — | — | None | — | — | JP | disclosed |
| JP-4110356-A | — | — | None | — | — | JP | disclosed |
| US-4101493-A | OIL IN WATER POLYMER EMULSION WITH A POLYACRYLIC ESTER | TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |
| US-4048035-A | UNSATURATED POLYESTER, MONOMER | MITSUBISHI RAYON CO., LTD. (JA) | 1977-09-13 | — | — | US | disclosed |
| US-3935173-A | POLYESTER TYPE OLIGO(METH) ACRYLATE | TOAGOSEI CHEMICAL INDUSTRIAL CO. LTD. (JA) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203884-A1 | DENTAL COMPOSITE MATERIALS COMPRISING TRICYCLIC PLASTICIZERS | CAD, PBRM1, PCBP1 | TSHR 3986/4885THRB 2856/4885ALDH1A1 2903/4885 |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | NCAPH, RCC1, NCAPD2 | TSHR 4596/4885THRB 4522/4885ALDH1A1 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.