SCHEMBL14727173

SCHEMBL14727173

C=Cc1ccc(COCCc2ccc(N(c3ccccc3)c3ccc(COCCOCc4ccc(N(c5ccc(CCOCc6ccc(C=C)cc6)cc5)c5ccc(CCOCc6ccc(C=C)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ALDH1A1 P00352 3/20 0.35
TSHR P16473 2/20 0.35
NAAA Q02083 1/20 0.33
INSR P06213 1/20 0.32
AKR1B10 O60218 1/20 0.32
AKR1B1 P15121 1/20 0.32
MAOB P27338 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KCNH2 Q12809 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14727120 0.97 PPARG (0.37) PPARGTDP1L3MBTL1ALDH1A1TSHR
SCHEMBL14727181 0.94 ALDH1A1 (0.34) PPARGTDP1L3MBTL1ALDH1A1KCNH2
SCHEMBL14730142 0.93 TDP1 (0.36) PPARGTDP1L3MBTL1ALDH1A1TSHR
SCHEMBL14727155 0.93 NAAA (0.39) PPARGTDP1L3MBTL1ALDH1A1TSHR
SCHEMBL14727169 0.92 NAAA (0.35) PPARGTDP1L3MBTL1ALDH1A1TSHR
SCHEMBL14727186 0.91 ALDH1A1 (0.34) PPARGTDP1L3MBTL1ALDH1A1KCNH2
SCHEMBL14727183 0.91 ALDH1A1 (0.34) PPARGTDP1L3MBTL1ALDH1A1KCNH2
SCHEMBL14727187 0.91 ALDH1A1 (0.34) PPARGTDP1L3MBTL1ALDH1A1TSHR
SCHEMBL14727143 0.91 NAAA (0.39) PPARGTDP1L3MBTL1ALDH1A1TSHR
SCHEMBL14727131 0.91 NAAA (0.39) PPARGTDP1L3MBTL1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8663883-B2 Charge-transporting film, photoelectric conversion device, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-04 US disclosed
US-20130052570-A1 CHARGE-TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed