SCHEMBL14727155

SCHEMBL14727155

C=Cc1ccc(COCCc2ccc(N(c3ccc(COCCOCc4ccc(N(c5ccc(CCOCc6ccc(C=C)cc6)cc5)c5ccc(-c6ccccc6)cc5)cc4)cc3)c3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.39
IDO1 P14902 2/20 0.36
AGXT P21549 2/20 0.36
PPARG P37231 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
FFAR1 O14842 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
UGCG Q16739 3/20 0.33
GBA2 Q9HCG7 3/20 0.33
GBA1 P04062 2/20 0.33
LCT P09848 2/20 0.33
SI P14410 2/20 0.33
POLB P06746 1/20 0.33
MGAM O43451 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14727143 0.97 NAAA (0.39) NAAAIDO1AGXTPPARGL3MBTL1
SCHEMBL14727131 0.97 NAAA (0.39) NAAAIDO1AGXTPPARGL3MBTL1
SCHEMBL14727129 0.95 L3MBTL1 (0.40) NAAAIDO1AGXTPPARGL3MBTL1
SCHEMBL14727169 0.94 NAAA (0.35) NAAAIDO1AGXTPPARGL3MBTL1
SCHEMBL14727173 0.93 PPARG (0.37) NAAAPPARGL3MBTL1TDP1MAPT
SCHEMBL14727126 0.92 NAAA (0.35) NAAAIDO1AGXTPPARGL3MBTL1
SCHEMBL14732704 0.91 NAAA (0.43) NAAAIDO1AGXTPPARGL3MBTL1
SCHEMBL14727188 0.91 ALDH1A1 (0.31) NAAAPPARGALDH1A1
SCHEMBL14727117 0.91 IDO1 (0.39) NAAAIDO1AGXTFFAR1POLB
SCHEMBL14727120 0.91 PPARG (0.37) PPARGL3MBTL1TDP1MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8663883-B2 Charge-transporting film, photoelectric conversion device, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-04 US disclosed
US-8663883-B2 Charge-transporting film, photoelectric conversion device, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-04 US disclosed
US-20130052570-A1 CHARGE-TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed
US-20130052570-A1 CHARGE-TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed